We are pleased to announce that a paper by Sr. Assist. Prof. Kubo, Ms. Sasaki (3rd-year medical student), and Prof. Oda has been published in the journal Molecular Biology of the Cell.
The study investigates the role of tubulin glycylation in ciliary and flagellar motility by generating a novel Chlamydomonas mutant lacking the monoglycylase TTLL3. The findings reveal that glycylated tubulin regulates ciliary motility by modulating outer arm dyneins. This significant insight highlights the impact of glycylation on ciliary function and provides a foundation for exploring cellular motility mechanisms and their implications in diseases associated with ciliary dysfunction.
